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Black Creek Canal virus : ウィキペディア英語版
Black Creek Canal virus

Black Creek Canal virus (BCCV) is a single-stranded, negative sense RNA virus species of New World Hantavirus. It was first isolated in cotton rats (Sigmodon hispidus) found in the Black Creek Canal area of Dade County, Florida in 1995. The discovery followed from an isolated case of Hantavirus pulmonary syndrome diagnosed in a Dade County resident.〔E. V. Ravkov, S. T. Nichol and R. W. Compans. Polarized entry and release in epithelial cells of Black Creek Canal virus, a New World hantavirus. J. Virology, Feb. 1997. Vol. 71, no 2. 1147-1154〕〔Zaki SR, Albers RC, Greer PW, Coffield LM, Armstrong LR, Khan AS, Khabbaz R, Peters CJ. Retrospective diagnosis of a 1983 case of fatal hantavirus pulmonary syndrome. Lancet. 1994 Apr 23;343(8904):1037–1038. 〕〔Zaki SR, Greer PW, Coffield LM, Goldsmith CS, Nolte KB, Foucar K, Feddersen RM, Zumwalt RE, Miller GL, Khan AS, et al. Hantavirus pulmonary syndrome. Pathogenesis of an emerging infectious disease. Am J Pathol. 1995 Mar;146(3):552–579.〕〔Rollin PE, Ksiazek TG, Elliott LH, Ravkov EV, Martin ML, Morzunov S, Livingstone W, Monroe M, Glass G, Ruo S, et al. Isolation of black creek canal virus, a new hantavirus from Sigmodon hispidus in Florida. J Med Virol. 1995 May;46(1):35–39.〕
== Natural reservoir ==
While several species are responsible for Hantavirus hemorrhagic fever syndrome (HFS) and Hantavirus pulmonary syndrome (HPS), each species of hantavirus is unique to a single reservoir. This makes host evolution and geography important factors in understanding transmission and prevention of spread of disease to humans. 〔Klein SL, Calisher CH.Emergence and persistence of hantaviruses.Curr Top Microbiol Immunol. 2007;315:217-52.〕

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